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About a dozen other people were wounded.

11 July 2013 02:19 (UTC +04:00)

A police escort was accompanying Shaikh's white armored sports utility vehicle when the attack took place. Police said an unidentified attacker walked up to the car and blew himself up just as Shaikh opened the door to get out.

No one immediately claimed responsibility for the attack, which took place on the eve of the start of the holy Muslim month of Ramadan that is observed in Pakistan from Thursday.

The latest wave of attacks across Pakistan has brought an end to a period of relative calm after Pakistan's first ever transition between elected civilian governments that brought Sharif to office for the third time in a May election.

Last weekend, at least five people were killed when a bomb ripped through a busy restaurant street in Lahore, wounding dozens as people sat to dinner in the old part of Sharif's home city.

On June 30, at least 28 people were killed in the southwestern city of Quetta when a suicide bomber attacked a largely Shi'ite Muslim neighborhood, highlighting growing sectarian tensions in the South Asian country of 180 million.

Shaikh - who had survived an earlier assassination attempt near his home in Karachi about a year ago - used to change his routes several times while travelling around one of Pakistan's most violent cities.

Like Zardari, he belonged to the Pakistan People's Party, which had been in power before the May election. Taliban-linked militants had previously targeted the secular party.

Both Zardari and Sharif have issued separate statements condemning the attack, a private television channel reported.

It was the first attack in Karachi since mid-June. At least nine people were killed when a bomb targeting the convoy of a senior judge exploded in the old city area. The judge survived. Pakistan-based Taliban claimed responsibility for that attack.