More than 60% of Putin's war chest has been frozen by sanctions but more needs to be done, Liz Truss has said, APA reports citing BBC.
The foreign secretary said "crippling" sanctions are pushing the Russian economy back "into the Soviet era".
More than $350bn (£266bn) of Russia's $604bn foreign currency reserves are unavailable to the regime, she added.
Her call for more to be done comes amid condemnation after images of bodies in the streets of Bucha, near Kyiv, emerged after Russian troops withdrew.
Ukrainian President Volodymyr Zelensky has warned he believes the worst atrocities committed by Russian forces are yet to be discovered, but Russia has denied killing civilians - claiming, without evidence, that Ukraine has staged such scenes.
Prime Minister Boris Johnson has released a video on social media, addressed to the Russian public, in which he accuses Russian troops of committing atrocities, including the massacre of civilians and the raping of women.