A source close to the Syrian government confirmed the strike and said there had been casualties and vehicles destroyed, Reuters reported.
The Syrian Observatory for Human Rights said the strike hit part of the Saeqa military camp near the town of Ayyash in western Deir al Zor province and wounded 13 military personnel in the first such incident since the coalition began its bombing campaign against Islamic State in Syria.
Deir al Zor province links Islamic State's de facto capital in Raqqa with territory controlled by the group in Iraq, and its oilfields are a major source of revenue for the group.