At least 12 civilians were killed Saturday in a blast near the airport of Aden, the Yemeni government's interim capital, APA reports quoting AFP.
"Twelve civilians were killed in an explosion" in the vicinity of Aden airport and "there are also serious injuries", said the official, who spoke on condition of anonymity, adding that the cause of the blast was unknown.
The explosion comes almost three weeks after six people were killed in a car-bomb attack that targeted Aden's governor, who survived.
AFP footage on Saturday showed people pulling out a body from a vehicle that had been completely destroyed, as firefighters put out flames nearby.
The internationally recognised government relocated to Aden from the capital Sanaa in 2014, forced out by the Huthis, who are fighting Saudi-backed Yemeni government loyalists.
A Saudi-led military coalition intervened in Yemen's war in 2015.
No one has yet claimed responsibility for Saturday's blast, which is the deadliest in the area since December last year when an attack targeting cabinet members ripped through Aden's airport.
At least 26 people, including three members of the International Committee of the Red Cross, were killed and scores were wounded when explosions rocked the airport as ministers disembarked from an aircraft.
All cabinet members were reported to be unharmed, in what some ministers charged was a Huthi attack.
In recent weeks, fighting has intensified around the government's sole remaining northern stronghold -- the city of Marib in the oil-rich province of the same name.
The coalition has said it has killed a total of around 2,000 rebels around the city in almost daily strikes since October 11.
Yemen is also home to Al-Qaeda in the Arabian Peninsula, which launches periodic attacks against both fighters aligned with the country's authorities and the insurgents.
Tens of thousands of people, mostly civilians, have been killed and millions displaced in Yemen's conflict, which the United Nations has called the world's worst humanitarian disaster.
At least 10 people were killed and 20 others injured in a car bomb blast near the airport in Yemen’s southern Aden city on Saturday, according to an official, APA reports quoting Anadolu Agency.
Airport spokesman Adel Hamran told Anadolu Agency that the bomb-laden vehicle exploded at the entrance of the international airport in the port city of Aden.
Among the casualties were security officers, he also said.
Nearby vehicles burst into flames as some houses were damaged due to the blast, he stated.
There is no claim of responsibility for the attack yet.
Aden, the temporary capital of Yemen, experiences regular attacks that target government officials and public figures.
Yemen has been engulfed by violence and instability since 2014, when Houthi rebels captured much of the country, including the capital Sanaa.
A Saudi-led coalition aimed at reinstating the Yemeni government has worsened the situation, causing one of the world’s worst man-made humanitarian crises with 233,000 people killed, nearly 80% or about 30 million needing humanitarian assistance and protection, and more than 13 million in danger of starvation, according to UN estimates.