Missiles have struck a city far from the eastern frontline, killing at least 22 people including three children, Ukrainian officials say, APA reports citing BBC.
Some 100 more were reported injured in the attack in Vinnytsia, to the south-west of Kyiv and a long way from the heart of the fighting in Donbas.
Three Russian missiles hit an office block and damaged residential buildings.
Ukrainian President Volodymyr Zelensky called it "an open act of terrorism".
The missiles hit the car park of the nine-storey office block at around 10:50 (07:50 GMT), Ukraine's State Emergency Service said. Residential buildings were also hit in the centre of Vinnytsia, which has a population of around 370,000.