The letter appeared aimed both at buttressing the campaign against Islamic State and nudging Iran’s religious leader closer to a nuclear deal.
Mr. Obama stressed to Mr. Khamenei that any cooperation on Islamic State was largely contingent on Iran reaching a comprehensive agreement with global powers on the future of Tehran’s nuclear program by a Nov. 24 diplomatic deadline, the same people say.
The October letter marked at least the fourth time Mr. Obama has written Iran’s most powerful political and religious leader since taking office in 2009 and pledging to engage with Tehran’s Islamist government.
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